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MYB deregulation from a EWSR1-MYB fusion at leukemic evolution of a JAK2(V617F) positive primary myelofibrosis

BACKGROUND: Although Philadelphia-negative myeloproliferative neoplasms (Ph-MPN) are usually not aggressive, the type and the number of molecular lesions impact greatly on leukemic transformation. Indeed, the molecular background underlying progression is still largely unexplored even though ASXL1,...

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Detalles Bibliográficos
Autores principales: Pierini, Tiziana, Di Giacomo, Danika, Pierini, Valentina, Gorello, Paolo, Barba, Gianluca, Lema Fernandez, Anair Graciela, Pellanera, Fabrizia, Iannotti, Tamara, Falzetti, Franca, La Starza, Roberta, Mecucci, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009546/
https://www.ncbi.nlm.nih.gov/pubmed/27594918
http://dx.doi.org/10.1186/s13039-016-0277-1