A simple gene set-based method accurately predicts the synergy of drug pairs

BACKGROUND: The advance in targeted therapy has greatly increased the effectiveness of clinical cancer therapy and reduced the cytotoxicity of treatments to normal cells. However, patients still suffer from cancer relapse due to the occurrence of drug resistance. It is of great need to explore poten...

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Detalles Bibliográficos
Autores principales: Hsu, Yu-Ching, Chiu, Yu-Chiao, Chen, Yidong, Hsiao, Tzu-Hung, Chuang, Eric Y.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009556/
https://www.ncbi.nlm.nih.gov/pubmed/27585722
http://dx.doi.org/10.1186/s12918-016-0310-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009556/
https://www.ncbi.nlm.nih.gov/pubmed/27585722
http://dx.doi.org/10.1186/s12918-016-0310-3

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