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A simple gene set-based method accurately predicts the synergy of drug pairs
BACKGROUND: The advance in targeted therapy has greatly increased the effectiveness of clinical cancer therapy and reduced the cytotoxicity of treatments to normal cells. However, patients still suffer from cancer relapse due to the occurrence of drug resistance. It is of great need to explore poten...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009556/ https://www.ncbi.nlm.nih.gov/pubmed/27585722 http://dx.doi.org/10.1186/s12918-016-0310-3 |