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Predicting existing targets for new drugs base on strategies for missing interactions

BACKGROUND: There has been paid more and more attention to supervised classification models in the area of predicting drug-target interactions (DTIs). However, in terms of classification, unavoidable missing DTIs in data would cause three issues which have not yet been addressed appropriately by for...

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Detalles Bibliográficos
Autores principales: Shi, Jian-Yu, Li, Jia-Xin, Lu, Hui-Meng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009565/
https://www.ncbi.nlm.nih.gov/pubmed/27585458
http://dx.doi.org/10.1186/s12859-016-1118-2