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Intra-discal injection of autologous, hypoxic cultured bone marrow-derived mesenchymal stem cells in five patients with chronic lower back pain: a long-term safety and feasibility study

BACKGROUND: Chronic low back pain due to disc degeneration represents a major social and economic burden worldwide. The current standard of care is limited to symptomatic relief and no current approved therapy promotes disc regeneration. Bone marrow-derived mesenchymal stem cells (MSCs) are easily a...

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Detalles Bibliográficos
Autores principales: Elabd, Christian, Centeno, Christopher J., Schultz, John R., Lutz, Gregory, Ichim, Thomas, Silva, Francisco J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009698/
https://www.ncbi.nlm.nih.gov/pubmed/27585696
http://dx.doi.org/10.1186/s12967-016-1015-5