Methylation of histone H4 lysine 20 by PR-Set7 ensures the integrity of late replicating sequence domains in Drosophila

The methylation state of lysine 20 on histone H4 (H4K20) has been linked to chromatin compaction, transcription, DNA repair and DNA replication. Monomethylation of H4K20 (H4K20me1) is mediated by the cell cycle-regulated histone methyltransferase PR-Set7. PR-Set7 depletion in mammalian cells results...

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Detalles Bibliográficos
Autores principales: Li, Yulong, Armstrong, Robin L., Duronio, Robert J., MacAlpine, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Gene regulation, Chromatin and Epigenetics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009726/
https://www.ncbi.nlm.nih.gov/pubmed/27131378
http://dx.doi.org/10.1093/nar/gkw333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009726/
https://www.ncbi.nlm.nih.gov/pubmed/27131378
http://dx.doi.org/10.1093/nar/gkw333

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