Widespread transcriptional gene inactivation initiated by a repair intermediate of 8-oxoguanine

DNA damage can significantly modulate expression of the affected genes either by direct structural interference with transcription components or as a collateral outcome of cellular repair attempts. Thus, DNA glycosylases of the base excision repair (BER) pathway have been implicated in negative tran...

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Detalles Bibliográficos
Autores principales: Allgayer, Julia, Kitsera, Nataliya, Bartelt, Solveig, Epe, Bernd, Khobta, Andriy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009734/
https://www.ncbi.nlm.nih.gov/pubmed/27220469
http://dx.doi.org/10.1093/nar/gkw473

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009734/
https://www.ncbi.nlm.nih.gov/pubmed/27220469
http://dx.doi.org/10.1093/nar/gkw473

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