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Widespread transcriptional gene inactivation initiated by a repair intermediate of 8-oxoguanine

DNA damage can significantly modulate expression of the affected genes either by direct structural interference with transcription components or as a collateral outcome of cellular repair attempts. Thus, DNA glycosylases of the base excision repair (BER) pathway have been implicated in negative tran...

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Detalles Bibliográficos
Autores principales:	Allgayer, Julia, Kitsera, Nataliya, Bartelt, Solveig, Epe, Bernd, Khobta, Andriy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009734/ https://www.ncbi.nlm.nih.gov/pubmed/27220469 http://dx.doi.org/10.1093/nar/gkw473

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