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The RNA-binding protein TTP is a global post-transcriptional regulator of feedback control in inflammation

RNA-binding proteins (RBPs) facilitate post-transcriptional control of eukaryotic gene expression at multiple levels. The RBP tristetraprolin (TTP/Zfp36) is a signal-induced phosphorylated anti-inflammatory protein guiding unstable mRNAs of pro-inflammatory proteins for degradation and preventing tr...

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Detalles Bibliográficos
Autores principales: Tiedje, Christopher, Diaz-Muñoz, Manuel D., Trulley, Philipp, Ahlfors, Helena, Laaß, Kathrin, Blackshear, Perry J., Turner, Martin, Gaestel, Matthias
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
RNA
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009735/
https://www.ncbi.nlm.nih.gov/pubmed/27220464
http://dx.doi.org/10.1093/nar/gkw474