Cargando…

The RNA-binding protein TTP is a global post-transcriptional regulator of feedback control in inflammation

RNA-binding proteins (RBPs) facilitate post-transcriptional control of eukaryotic gene expression at multiple levels. The RBP tristetraprolin (TTP/Zfp36) is a signal-induced phosphorylated anti-inflammatory protein guiding unstable mRNAs of pro-inflammatory proteins for degradation and preventing tr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tiedje, Christopher, Diaz-Muñoz, Manuel D., Trulley, Philipp, Ahlfors, Helena, Laaß, Kathrin, Blackshear, Perry J., Turner, Martin, Gaestel, Matthias
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2016
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009735/ https://www.ncbi.nlm.nih.gov/pubmed/27220464 http://dx.doi.org/10.1093/nar/gkw474

Ejemplares similares

A role for transportin in deposition of TTP to cytoplasmic RNA granules and mRNA decay
por: Chang, Wei-Lun, et al.
Publicado: (2009)

The p38/MK2-Driven Exchange between Tristetraprolin and HuR Regulates AU–Rich Element–Dependent Translation
por: Tiedje, Christopher, et al.
Publicado: (2012)

The mRNA-binding Protein TTP/ZFP36 in Hepatocarcinogenesis and Hepatocellular Carcinoma
por: Kröhler, Tarek, et al.
Publicado: (2019)

Reciprocal regulation of glycine-rich RNA-binding proteins via an interlocked feedback loop coupling alternative splicing to nonsense-mediated decay in Arabidopsis
por: Schöning, Jan C., et al.
Publicado: (2008)

Identification of the Rps28 binding motif from yeast Edc3 involved in the autoregulatory feedback loop controlling RPS28B mRNA decay
por: Kolesnikova, Olga, et al.
Publicado: (2013)

The feedback control of UPF3 is crucial for RNA surveillance in plants
por: Degtiar, Evgeniya, et al.
Publicado: (2015)

Nucleotide modifications within bacterial messenger RNAs regulate their translation and are able to rewire the genetic code
por: Hoernes, Thomas Philipp, et al.
Publicado: (2016)

The Crc global regulator binds to an unpaired A-rich motif at the Pseudomonas putida alkS mRNA coding sequence and inhibits translation initiation
por: Moreno, Renata, et al.
Publicado: (2009)

CWC22-dependent pre-mRNA splicing and eIF4A3 binding enables global deposition of exon junction complexes
por: Steckelberg, Anna-Lena, et al.
Publicado: (2015)

TDP-43 regulates global translational yield by splicing of exon junction complex component SKAR
por: Fiesel, Fabienne C., et al.
Publicado: (2012)

Post-transcriptional regulation of satellite cell quiescence by TTP-mediated mRNA decay
por: Hausburg, Melissa A, et al.
Publicado: (2015)

Generation of functionally distinct isoforms of PTBP3 by alternative splicing and translation initiation
por: Tan, Lit-Yeen, et al.
Publicado: (2015)

The landscape of the non-canonical RNA-binding site of Gemin5 unveils a feedback loop counteracting the negative effect on translation
por: Francisco-Velilla, Rosario, et al.
Publicado: (2018)

Human ribosomal protein S13 regulates expression of its own gene at the splicing step by a feedback mechanism
por: Malygin, Alexey A., et al.
Publicado: (2007)

RNA interactome capture in Escherichia coli globally identifies RNA-binding proteins
por: Stenum, Thomas Søndergaard, et al.
Publicado: (2023)

Comparative Analysis of Two Gene-Targeting Approaches Challenges the Tumor-Suppressive Role of the Protein Kinase MK5/PRAK
por: Ronkina, Natalia, et al.
Publicado: (2015)

Magnesium-binding architectures in RNA crystal structures: validation, binding preferences, classification and motif detection
por: Zheng, Heping, et al.
Publicado: (2015)

Conformational dynamics of the tetracycline-binding aptamer
por: Förster, Ute, et al.
Publicado: (2012)

An improved definition of the RNA-binding specificity of SECIS-binding protein 2, an essential component of the selenocysteine incorporation machinery
por: Cléry, A., et al.
Publicado: (2007)

A short motif in Drosophila SECIS Binding Protein 2 provides differential binding affinity to SECIS RNA hairpins
por: Takeuchi, Akiko, et al.
Publicado: (2009)

Codeine-binding RNA aptamers and rapid determination of their binding constants using a direct coupling surface plasmon resonance assay
por: Win, Maung Nyan, et al.
Publicado: (2006)

Global regulation of alternative splicing during myogenic differentiation
por: Bland, Christopher S., et al.
Publicado: (2010)

Global analysis of mRNA stability in Mycobacterium tuberculosis
por: Rustad, Tige R., et al.
Publicado: (2013)

A highly specialized flavin mononucleotide riboswitch responds differently to similar ligands and confers roseoflavin resistance to Streptomyces davawensis
por: Pedrolli, Danielle Biscaro, et al.
Publicado: (2012)

RNA-binding specificity of E. coli NusA
por: Prasch, Stefan, et al.
Publicado: (2009)

Identification and characterization of RNA guanine-quadruplex binding proteins
por: von Hacht, Annekathrin, et al.
Publicado: (2014)

Nucleic acid-binding specificity of human FUS protein
por: Wang, Xueyin, et al.
Publicado: (2015)

Dynamic profiling of double-stranded RNA binding proteins
por: Wang, Xinlei, et al.
Publicado: (2015)

Coordination of two sequential ester-transfer reactions: exogenous guanosine binding promotes the subsequent ωG binding to a group I intron
por: Bao, Penghui, et al.
Publicado: (2008)

Binding of the 5′-untranslated region of coronavirus RNA to zinc finger CCHC-type and RNA-binding motif 1 enhances viral replication and transcription
por: Tan, Yong Wah, et al.
Publicado: (2012)

The RNA-binding domain of influenzavirus non-structural protein-1 cooperatively binds to virus-specific RNA sequences in a structure-dependent manner
por: Marc, Daniel, et al.
Publicado: (2013)

A global view of the nonprotein-coding transcriptome in Plasmodium falciparum
por: Raabe, Carsten A., et al.
Publicado: (2010)

Escherichia coli ribosomal protein L20 binds as a single monomer to its own mRNA bearing two potential binding sites
por: Allemand, F., et al.
Publicado: (2007)

Direct binding of the Alu binding protein dimer SRP9/14 to 40S ribosomal subunits promotes stress granule formation and is regulated by Alu RNA
por: Berger, A., et al.
Publicado: (2014)

Competition for RISC binding predicts in vitro potency of siRNA
por: Koller, Erich, et al.
Publicado: (2006)

Binding of aminoglycoside antibiotics to helix 69 of 23S rRNA
por: Scheunemann, Ann E., et al.
Publicado: (2010)

Contribution of ribosomal residues to P-site tRNA binding
por: Shoji, Shinichiro, et al.
Publicado: (2009)

Investigating the entire course of telithromycin binding to Escherichia coli ribosomes
por: Kostopoulou, Ourania N., et al.
Publicado: (2012)

Identification and characterization of the RNA binding surface of the pentatricopeptide repeat protein
por: Kobayashi, Keiko, et al.
Publicado: (2012)

Conformational change of single-stranded RNAs induced by liposome binding
por: Suga, Keishi, et al.
Publicado: (2011)

Cannot write session to /tmp/vufind_sessions/sess_f8p9bpous68tjbp1mg8rj3p8id