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Molecular events during translocation and proofreading extracted from 200 static structures of DNA polymerase
DNA polymerases in family B are workhorses of DNA replication that carry out the bulk of the job at a high speed with high accuracy. A polymerase in this family relies on a built-in exonuclease for proofreading. It has not been observed at the atomic resolution how the polymerase advances one nucleo...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009745/ https://www.ncbi.nlm.nih.gov/pubmed/27325739 http://dx.doi.org/10.1093/nar/gkw555 |