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Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP

MicroRNAs (miRs) have emerged as key biological effectors in human health and disease. These small noncoding RNAs are incorporated into Argonaute (Ago) proteins, where they direct post-transcriptional gene silencing via base-pairing with target transcripts. Although miRs have become intriguing biolo...

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Detalles Bibliográficos
Autores principales: Spengler, Ryan M., Zhang, Xiaoming, Cheng, Congsheng, McLendon, Jared M., Skeie, Jessica M., Johnson, Frances L., Davidson, Beverly L., Boudreau, Ryan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009757/
https://www.ncbi.nlm.nih.gov/pubmed/27418678
http://dx.doi.org/10.1093/nar/gkw640