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Elucidation of transcriptome-wide microRNA binding sites in human cardiac tissues by Ago2 HITS-CLIP
MicroRNAs (miRs) have emerged as key biological effectors in human health and disease. These small noncoding RNAs are incorporated into Argonaute (Ago) proteins, where they direct post-transcriptional gene silencing via base-pairing with target transcripts. Although miRs have become intriguing biolo...
Autores principales: | Spengler, Ryan M., Zhang, Xiaoming, Cheng, Congsheng, McLendon, Jared M., Skeie, Jessica M., Johnson, Frances L., Davidson, Beverly L., Boudreau, Ryan L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009757/ https://www.ncbi.nlm.nih.gov/pubmed/27418678 http://dx.doi.org/10.1093/nar/gkw640 |
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