IFNλ is a potent anti‐influenza therapeutic without the inflammatory side effects of IFNα treatment

Influenza A virus (IAV)‐induced severe disease is characterized by infected lung epithelia, robust inflammatory responses and acute lung injury. Since type I interferon (IFNαβ) and type III interferon (IFNλ) are potent antiviral cytokines with immunomodulatory potential, we assessed their efficacy a...

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Detalles Bibliográficos
Autores principales: Davidson, Sophia, McCabe, Teresa M, Crotta, Stefania, Gad, Hans Henrik, Hessel, Edith M, Beinke, Soren, Hartmann, Rune, Wack, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009813/
https://www.ncbi.nlm.nih.gov/pubmed/27520969
http://dx.doi.org/10.15252/emmm.201606413

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009813/
https://www.ncbi.nlm.nih.gov/pubmed/27520969
http://dx.doi.org/10.15252/emmm.201606413

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