Cargando…
Modeling the functional state of the reverse transcriptase of hepatitis B virus and its application to probing drug-protein interaction
BACKGROUND: Herein, the predicted atomic structures of five representative sequence variants of the reverse transcriptase protein (RT) of hepatitis B virus (HBV), sampled from patients with rapid or slow response to tenofovir disoproxil fumarate (TDF) treatment, have been examined to identify struct...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009823/ https://www.ncbi.nlm.nih.gov/pubmed/27587008 http://dx.doi.org/10.1186/s12859-016-1116-4 |