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Increased expression of Trpv1 in peripheral terminals mediates thermal nociception in Fabry disease mouse model

Fabry disease is a X-linked lysosomal storage disorder caused by deficient function of the alpha-galactosidase A (α-GalA) enzyme. α-GalA deficiency leads to multisystemic clinical manifestations caused by the preferential accumulation of globotriaosylceramide (Gb3) in the endothelium and vascular sm...

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Detalles Bibliográficos
Autores principales: Lakomá, Jarmila, Rimondini, Roberto, Ferrer Montiel, Antonio, Donadio, Vincenzo, Liguori, Rocco, Caprini, Marco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009828/
https://www.ncbi.nlm.nih.gov/pubmed/27531673
http://dx.doi.org/10.1177/1744806916663729