Protection associated with a TB vaccine is linked to increased frequency of Ag85A-specific CD4(+) T cells but no increase in avidity for Ag85A

There is a need to improve the efficacy of Bacille Calmette-Guérin (BCG) vaccination against tuberculosis in humans and cattle. Previously, we found boosting BCG-primed cows with recombinant human type 5 adenovirus expressing antigen 85A (Ad5-85A) increased protection against Mycobacterium bovis inf...

Descripción completa

Detalles Bibliográficos
Autores principales: Metcalfe, Hannah J., Steinbach, Sabine, Jones, Gareth J., Connelley, Tim, Morrison, W. Ivan, Vordermeier, Martin, Villarreal-Ramos, Bernardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009893/
https://www.ncbi.nlm.nih.gov/pubmed/27498622
http://dx.doi.org/10.1016/j.vaccine.2016.07.055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009893/
https://www.ncbi.nlm.nih.gov/pubmed/27498622
http://dx.doi.org/10.1016/j.vaccine.2016.07.055

Ejemplares similares