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Upregulation of KSRP by miR-27b provides IFN-γ-induced post-transcriptional regulation of CX3CL1 in liver epithelial cells

Aberrant cellular responses to pro-inflammatory cytokines, such as IFN-γ, are pathogenic features in many chronic inflammatory diseases. A variety of feedback regulatory pathways have evolved to prevent an inappropriate cellular reaction to these pro-inflammatory cytokines. CX3CL1 is a unique chemok...

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Detalles Bibliográficos
Autores principales: Xia, Zijie, Lu, Yajing, Li, Xiaoqing, Mao, Tiebo, Chen, Xian-Ming, Zhou, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5009954/
https://www.ncbi.nlm.nih.gov/pubmed/26631623
http://dx.doi.org/10.1038/srep17590