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Network analysis identifies Rv0324 and Rv0880 as regulators of bedaquiline tolerance in Mycobacterium tuberculosis

Resilience of Mycobacterium tuberculosis (MTB) emerges from its ability to effectively counteract immunological, environmental, and antitubercular challenges. Here, we demonstrate that MTB can tolerate drug treatment by adopting a tolerant state that can be deciphered through systems analysis of its...

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Detalles Bibliográficos
Autores principales: Peterson, Eliza J.R., Ma, Shuyi, Sherman, David R., Baliga, Nitin S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010021/
https://www.ncbi.nlm.nih.gov/pubmed/27573104
http://dx.doi.org/10.1038/nmicrobiol.2016.78