Mammalian Brain Development is Accompanied by a Dramatic Increase in Bipolar DNA Methylation

DNA methylation is an epigenetic mechanism critical for tissue development and cell specification. Mammalian brains consist of many different types of cells with assumedly distinct DNA methylation profiles, and thus some genomic loci may demonstrate bipolar DNA methylation pattern, i.e. hypermethyla...

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Detalles Bibliográficos
Autores principales: Sun, Ming-an, Sun, Zhixiong, Wu, Xiaowei, Rajaram, Veena, Keimig, David, Lim, Jessica, Zhu, Hongxiao, Xie, Hehuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010034/
https://www.ncbi.nlm.nih.gov/pubmed/27585862
http://dx.doi.org/10.1038/srep32298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010034/
https://www.ncbi.nlm.nih.gov/pubmed/27585862
http://dx.doi.org/10.1038/srep32298

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