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Spotlight on tocilizumab and its potential in the treatment of systemic sclerosis
Systemic sclerosis (SSc) is a multisystem disease characterized by extensive collagen deposition in skin and internal organs, fibrointimal microvasculopathy, and activation of the immune system. T cells and B cells can promote fibrosis in SSc. Interleukin (IL)-6 is implicated in the pathogenesis of...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove Medical Press
2016
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010079/ https://www.ncbi.nlm.nih.gov/pubmed/27621593 http://dx.doi.org/10.2147/DDDT.S99696 |