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Interactions between Activation and Repolarization Restitution Properties in the Intact Human Heart: In-Vivo Whole-Heart Data and Mathematical Description

BACKGROUND: The restitution of the action potential duration (APDR) and conduction velocity (CVR) are mechanisms whereby cardiac excitation and repolarization adapt to changes in heart rate. They modulate the vulnerability to dangerous arrhythmia, but the mechanistic link between restitution and arr...

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Detalles Bibliográficos
Autores principales: Orini, Michele, Taggart, Peter, Srinivasan, Neil, Hayward, Martin, Lambiase, Pier D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010207/
https://www.ncbi.nlm.nih.gov/pubmed/27588688
http://dx.doi.org/10.1371/journal.pone.0161765