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Oral Vaccination with Attenuated Salmonella typhimurium-Delivered TsPmy DNA Vaccine Elicits Protective Immunity against Trichinella spiralis in BALB/c Mice

BACKGROUND: Our previous studies showed that Trichinella spiralis paramyosin (TsPmy) is an immunomodulatory protein that inhibits complement C1q and C8/C9 to evade host complement attack. Vaccination with recombinant TsPmy protein induced protective immunity against T. spiralis larval challenge. Due...

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Detalles Bibliográficos
Autores principales: Wang, Lei, Wang, Xiaohuan, Bi, Kuo, Sun, Ximeng, Yang, Jing, Gu, Yuan, Huang, Jingjing, Zhan, Bin, Zhu, Xinping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010209/
https://www.ncbi.nlm.nih.gov/pubmed/27589591
http://dx.doi.org/10.1371/journal.pntd.0004952