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Driving the Model to Its Limit: Profile Likelihood Based Model Reduction
In systems biology, one of the major tasks is to tailor model complexity to information content of the data. A useful model should describe the data and produce well-determined parameter estimates and predictions. Too small of a model will not be able to describe the data whereas a model which is to...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010240/ https://www.ncbi.nlm.nih.gov/pubmed/27588423 http://dx.doi.org/10.1371/journal.pone.0162366 |