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Characterization of a Non-Canonical Signal Peptidase Cleavage Site in a Replication Protein from Tomato Ringspot Virus

The NTB-VPg polyprotein from tomato ringspot virus is an integral membrane replication protein associated with endoplasmic reticulum membranes. A signal peptidase (SPase) cleavage was previously detected in the C-terminal region of NTB-VPg downstream of a 14 amino acid (aa)-long hydrophobic region (...

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Detalles Bibliográficos
Autores principales: Wei, Ting, Chisholm, Joan, Sanfaçon, Hélène
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010249/
https://www.ncbi.nlm.nih.gov/pubmed/27589230
http://dx.doi.org/10.1371/journal.pone.0162223