Reverse Chemical Genetics: Comprehensive Fitness Profiling Reveals the Spectrum of Drug Target Interactions

The emergence and prevalence of drug resistance demands streamlined strategies to identify drug resistant variants in a fast, systematic and cost-effective way. Methods commonly used to understand and predict drug resistance rely on limited clinical studies from patients who are refractory to drugs...

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Detalles Bibliográficos
Autores principales: Wong, Lai H., Sinha, Sunita, Bergeron, Julien R., Mellor, Joseph C., Giaever, Guri, Flaherty, Patrick, Nislow, Corey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010250/
https://www.ncbi.nlm.nih.gov/pubmed/27588687
http://dx.doi.org/10.1371/journal.pgen.1006275

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010250/
https://www.ncbi.nlm.nih.gov/pubmed/27588687
http://dx.doi.org/10.1371/journal.pgen.1006275

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