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Impaired Tight Junctions in Atopic Dermatitis Skin and in a Skin-Equivalent Model Treated with Interleukin-17

Tight junction (TJ) dysfunction in the stratum granulosum leads to aberrant barrier function of the stratum corneum (SC) in the epidermis. However, it is unclear whether TJs are perturbed in atopic dermatitis (AD), a representative aberrant SC-related skin disease, and whether some factors related t...

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Detalles Bibliográficos
Autores principales: Yuki, Takuo, Tobiishi, Megumi, Kusaka-Kikushima, Ayumi, Ota, Yukiko, Tokura, Yoshiki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010286/
https://www.ncbi.nlm.nih.gov/pubmed/27588419
http://dx.doi.org/10.1371/journal.pone.0161759