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Nonstructural Proteins Are Preferential Positive Selection Targets in Zika Virus and Related Flaviviruses

The Flavivirus genus comprises several human pathogens such as dengue virus (DENV), Japanese encephalitis virus (JEV), and Zika virus (ZIKV). Although ZIKV usually causes mild symptoms, growing evidence is linking it to congenital birth defects and to increased risk of Guillain-Barré syndrome. ZIKV...

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Detalles Bibliográficos
Autores principales: Sironi, Manuela, Forni, Diego, Clerici, Mario, Cagliani, Rachele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010288/
https://www.ncbi.nlm.nih.gov/pubmed/27588756
http://dx.doi.org/10.1371/journal.pntd.0004978