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Effects of Tributyltin Chloride on Cybrids with or without an ATP Synthase Pathologic Mutation

BACKGROUND: The oxidative phosphorylation system (OXPHOS) includes nuclear chromosome (nDNA)– and mitochondrial DNA (mtDNA)–encoded polypeptides. Many rare OXPHOS disorders, such as striatal necrosis syndromes, are caused by genetic mutations. Despite important advances in sequencing procedures, cau...

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Detalles Bibliográficos
Autores principales: López-Gallardo, Ester, Llobet, Laura, Emperador, Sonia, Montoya, Julio, Ruiz-Pesini, Eduardo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010394/
https://www.ncbi.nlm.nih.gov/pubmed/27129022
http://dx.doi.org/10.1289/EHP182