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Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbations
In neurological disorders, both acute and chronic neural stress can disrupt cellular proteostasis, resulting in the generation of pathological protein. However in most cases, neurons adapt to these proteostatic perturbations by activating a range of cellular protective and repair responses, thus mai...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier/North-Holland Biomedical Press
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010532/ https://www.ncbi.nlm.nih.gov/pubmed/26923166 http://dx.doi.org/10.1016/j.brainres.2016.02.033 |