Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbations

In neurological disorders, both acute and chronic neural stress can disrupt cellular proteostasis, resulting in the generation of pathological protein. However in most cases, neurons adapt to these proteostatic perturbations by activating a range of cellular protective and repair responses, thus mai...

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Detalles Bibliográficos
Autores principales: Mollereau, B., Rzechorzek, N.M., Roussel, B.D., Sedru, M., Van den Brink, D.M., Bailly-Maitre, B., Palladino, F., Medinas, D.B., Domingos, P.M., Hunot, S., Chandran, S., Birman, S., Baron, T., Vivien, D., Duarte, C.B., Ryoo, H.D., Steller, H., Urano, F., Chevet, E., Kroemer, G., Ciechanover, A., Calabrese, E.J., Kaufman, R.J., Hetz, C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier/North-Holland Biomedical Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010532/
https://www.ncbi.nlm.nih.gov/pubmed/26923166
http://dx.doi.org/10.1016/j.brainres.2016.02.033

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