Investigating the KNDy Hypothesis in Humans by Coadministration of Kisspeptin, Neurokinin B, and Naltrexone in Men

CONTEXT: A subpopulation of hypothalamic neurons colocalize three neuropeptides, namely kisspeptin, neurokinin B (NKB), and dynorphin, collectively termed KNDy neurons. Animal studies suggest they interact to affect pulsatile GnRH release (KNDy hypothesis); kisspeptin stimulates, NKB modulates, and...

Descripción completa

Detalles Bibliográficos
Autores principales: Narayanaswamy, Shakunthala, Prague, Julia K., Jayasena, Channa N., Papadopoulou, Deborah A., Mizamtsidi, Maria, Shah, Amar J., Bassett, Paul, Comninos, Alexander N., Abbara, Ali, Bloom, Stephen R., Veldhuis, Johannes D., Dhillo, Waljit S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Endocrine Society 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010567/
https://www.ncbi.nlm.nih.gov/pubmed/27379743
http://dx.doi.org/10.1210/jc.2016-1911

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010567/
https://www.ncbi.nlm.nih.gov/pubmed/27379743
http://dx.doi.org/10.1210/jc.2016-1911

Ejemplares similares