Tilting the lasso by knowledge-based post-processing

BACKGROUND: It is useful to incorporate biological knowledge on the role of genetic determinants in predicting an outcome. It is, however, not always feasible to fully elicit this information when the number of determinants is large. We present an approach to overcome this difficulty. First, using h...

Descripción completa

Detalles Bibliográficos
Autores principales: Tharmaratnam, Kukatharmini, Sperrin, Matthew, Jaki, Thomas, Reppe, Sjur, Frigessi, Arnoldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010709/
https://www.ncbi.nlm.nih.gov/pubmed/27590269
http://dx.doi.org/10.1186/s12859-016-1210-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010709/
https://www.ncbi.nlm.nih.gov/pubmed/27590269
http://dx.doi.org/10.1186/s12859-016-1210-7

Ejemplares similares