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Tilting the lasso by knowledge-based post-processing
BACKGROUND: It is useful to incorporate biological knowledge on the role of genetic determinants in predicting an outcome. It is, however, not always feasible to fully elicit this information when the number of determinants is large. We present an approach to overcome this difficulty. First, using h...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010709/ https://www.ncbi.nlm.nih.gov/pubmed/27590269 http://dx.doi.org/10.1186/s12859-016-1210-7 |