Associations of genetic polymorphisms of the transporters organic cation transporter 2 (OCT2), multidrug and toxin extrusion 1 (MATE1), and ATP-binding cassette subfamily C member 2 (ABCC2) with platinum-based chemotherapy response and toxicity in non-small cell lung cancer patients

BACKGROUND: Platinum-based chemotherapy is the first-line treatment of non-small cell lung cancer (NSCLC); it is therefore important to discover biomarkers that can be used to predict the efficacy and toxicity of this treatment. Four important transporter genes are expressed in the kidney, including...

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Detalles Bibliográficos
Autores principales: Qian, Chen-Yue, Zheng, Yi, Wang, Ying, Chen, Juan, Liu, Jun-Yan, Zhou, Hong-Hao, Yin, Ji-Ye, Liu, Zhao-Qian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010769/
https://www.ncbi.nlm.nih.gov/pubmed/27590272
http://dx.doi.org/10.1186/s40880-016-0145-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010769/
https://www.ncbi.nlm.nih.gov/pubmed/27590272
http://dx.doi.org/10.1186/s40880-016-0145-8

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