Undefined familial colorectal cancer and the role of pleiotropism in cancer susceptibility genes

Although family history is a major risk factor for colorectal cancer (CRC) a genetic diagnosis cannot be obtained in over 50 % of familial cases when screened for known CRC cancer susceptibility genes. The genetics of undefined-familial CRC is complex and recent studies have implied additional clini...

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Detalles Bibliográficos
Autores principales: Dobbins, Sara E., Broderick, Peter, Chubb, Daniel, Kinnersley, Ben, Sherborne, Amy L., Houlston, Richard S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Netherlands 2016
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010824/
https://www.ncbi.nlm.nih.gov/pubmed/27356891
http://dx.doi.org/10.1007/s10689-016-9914-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010824/
https://www.ncbi.nlm.nih.gov/pubmed/27356891
http://dx.doi.org/10.1007/s10689-016-9914-4

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