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Undefined familial colorectal cancer and the role of pleiotropism in cancer susceptibility genes
Although family history is a major risk factor for colorectal cancer (CRC) a genetic diagnosis cannot be obtained in over 50 % of familial cases when screened for known CRC cancer susceptibility genes. The genetics of undefined-familial CRC is complex and recent studies have implied additional clini...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Netherlands
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010824/ https://www.ncbi.nlm.nih.gov/pubmed/27356891 http://dx.doi.org/10.1007/s10689-016-9914-4 |