Genetic variation in MHC proteins is associated with T cell receptor expression biases

Within each individual, a highly diverse T cell receptor (TCR) repertoire interacts with peptides presented by major histocompatibility complex (MHC) molecules. Despite extensive research, it remains controversial whether germline-encoded TCR-MHC contacts promote TCR-MHC specificity and if so, wheth...

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Detalles Bibliográficos
Autores principales: Sharon, Eilon, Sibener, Leah V., Battle, Alexis, Fraser, Hunter B., Garcia, K. Christopher, Pritchard, Jonathan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010864/
https://www.ncbi.nlm.nih.gov/pubmed/27479906
http://dx.doi.org/10.1038/ng.3625

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5010864/
https://www.ncbi.nlm.nih.gov/pubmed/27479906
http://dx.doi.org/10.1038/ng.3625

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