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Quercetin affects glutathione levels and redox ratio in human aortic endothelial cells not through oxidation but formation and cellular export of quercetin-glutathione conjugates and upregulation of glutamate-cysteine ligase

Endothelial dysfunction due to vascular inflammation and oxidative stress critically contributes to the etiology of atherosclerosis. The intracellular redox environment plays a key role in regulating endothelial cell function and is intimately linked to cellular thiol status, including and foremost...

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Detalles Bibliográficos
Autores principales: Li, Chuan, Zhang, Wei-Jian, Choi, Jaewoo, Frei, Balz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011167/
https://www.ncbi.nlm.nih.gov/pubmed/27572418
http://dx.doi.org/10.1016/j.redox.2016.08.012