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Cerebral blood flow in presymptomatic MAPT and GRN mutation carriers: A longitudinal arterial spin labeling study()

OBJECTIVE: Frontotemporal dementia (FTD) is characterized by behavioral disturbances and language problems. Familial forms can be caused by genetic defects in microtubule-associated protein tau (MAPT), progranulin (GRN), and C9orf72. In light of upcoming clinical trials with potential disease-modify...

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Detalles Bibliográficos
Autores principales: Dopper, Elise G.P., Chalos, Vicky, Ghariq, Eidrees, den Heijer, Tom, Hafkemeijer, Anne, Jiskoot, Lize C., de Koning, Inge, Seelaar, Harro, van Minkelen, Rick, van Osch, Matthias J.P., Rombouts, Serge A.R.B., van Swieten, John C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011170/
https://www.ncbi.nlm.nih.gov/pubmed/27625986
http://dx.doi.org/10.1016/j.nicl.2016.08.001