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A 90-Day Oral Toxicological Evaluation of the Methylurate Purine Alkaloid Theacrine

A 90-day repeated-dose oral toxicological evaluation was conducted according to GLP and OECD guidelines on the methylurate purine alkaloid theacrine, which is found naturally in certain plants. Four groups of Hsd.Brl.Han Wistar rats (ten/sex/group) were administered theacrine by gavage doses of 0 (v...

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Detalles Bibliográficos
Autores principales: Clewell, Amy, Hirka, Gábor, Glávits, Róbert, Palmer, Philip A., Endres, John R., Murbach, Timothy S., Marx, Tennille, Pasics Szakonyiné, Ilona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011229/
https://www.ncbi.nlm.nih.gov/pubmed/27635133
http://dx.doi.org/10.1155/2016/6206859