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Candidate SNP Markers of Chronopathologies Are Predicted by a Significant Change in the Affinity of TATA-Binding Protein for Human Gene Promoters

Variations in human genome (e.g., single nucleotide polymorphisms, SNPs) may be associated with hereditary diseases, their complications, comorbidities, and drug responses. Using Web service SNP_TATA_Comparator presented in our previous paper, here we analyzed immediate surroundings of known SNP mar...

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Detalles Bibliográficos
Autores principales: Ponomarenko, Petr, Rasskazov, Dmitry, Suslov, Valentin, Sharypova, Ekaterina, Savinkova, Ludmila, Podkolodnaya, Olga, Podkolodny, Nikolay L., Tverdokhleb, Natalya N., Chadaeva, Irina, Ponomarenko, Mikhail, Kolchanov, Nikolay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011241/
https://www.ncbi.nlm.nih.gov/pubmed/27635400
http://dx.doi.org/10.1155/2016/8642703