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Knockdown of the M2 Isoform of Pyruvate Kinase (PKM2) with shRNA Enhances the Effect of Docetaxel in Human NSCLC Cell Lines In Vitro

PURPOSE: The aim of our study was to explore the relationships between the M2 isoform of pyruvate kinase (PKM2) and the sensitivity of human non-small cell lung cancer (NSCLC) cells to docetaxel in vitro. MATERIALS AND METHODS: With the method of plasmid transfection, we silenced the expression of P...

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Detalles Bibliográficos
Autores principales: Yuan, Sujuan, Qiao, Tiankui, Zhuang, Xibing, Chen, Wei, Xing, Na, Zhang, Qi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Yonsei University College of Medicine 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011261/
https://www.ncbi.nlm.nih.gov/pubmed/27593857
http://dx.doi.org/10.3349/ymj.2016.57.6.1312