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Chlorpyrifos Toxicity in Mouse Cultured Cerebellar Granule Neurons at Different Stages of Development: Additive Effect on Glutamate-Induced Excitotoxicity

OBJECTIVE: Chlorpyrifos (CPF) is a neurotoxic organophosphorus (OP) insecticide. Its mechanism of action includes oxidative stress, excitotoxicity, and inhibition of the acetylcholinesterase enzyme (AChE). The aim of the present study is to investigate CPF toxicity in mature and immature cerebellar...

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Detalles Bibliográficos
Autores principales: Amani, Nahid, Soodi, Maliheh, Daraei, Bahram, Dashti, Abolfazl
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2016
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011335/
https://www.ncbi.nlm.nih.gov/pubmed/27602329