A high throughput drug screening assay to identify compounds that promote oligodendrocyte differentiation using acutely dissociated and purified oligodendrocyte precursor cells

BACKGROUND: Multiple sclerosis is caused by an autoimmune response resulting in demyelination and neural degeneration. The adult central nervous system has the capacity to remyelinate axons in part through the generation of new oligodendrocytes (OLs). To identify clinical candidate compounds that ma...

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Detalles Bibliográficos
Autores principales: Lariosa-Willingham, Karen D., Rosler, Elen S., Tung, Jay S., Dugas, Jason C., Collins, Tassie L., Leonoudakis, Dmitri
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Technical Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011342/
https://www.ncbi.nlm.nih.gov/pubmed/27592856
http://dx.doi.org/10.1186/s13104-016-2220-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011342/
https://www.ncbi.nlm.nih.gov/pubmed/27592856
http://dx.doi.org/10.1186/s13104-016-2220-2

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