Generation of a new transgenic mouse model for assessment of tau gene silencing therapies

BACKGROUND: Targeting the expression of genes has emerged as a potentially viable therapeutic approach to human disease. In Alzheimer’s disease, therapies that silence the expression of tau could be a viable strategy to slow disease progression. METHODS: We produced a novel strain of transgenic mice...

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Detalles Bibliográficos
Autores principales: Fromholt, Susan, Reitano, Christian, Brown, Hilda, Lewis, Jada, Borchelt, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011353/
https://www.ncbi.nlm.nih.gov/pubmed/27593210
http://dx.doi.org/10.1186/s13195-016-0202-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011353/
https://www.ncbi.nlm.nih.gov/pubmed/27593210
http://dx.doi.org/10.1186/s13195-016-0202-1

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