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Ganglioside GM3 synthase depletion reverses neuropathic pain and small fiber neuropathy in diet-induced diabetic mice
BACKGROUND: Small fiber neuropathy is a well-recognized complication of type 2 diabetes and has been shown to be responsible for both neuropathic pain and impaired wound healing. In previous studies, we have demonstrated that ganglioside GM3 depletion by knockdown of GM3 synthase fully reverses impa...
Autores principales: | Menichella, Daniela M, Jayaraj, Nirupa D, Wilson, Heather M, Ren, Dongjun, Flood, Kelsey, Wang, Xiao-Qi, Shum, Andrew, Miller, Richard J, Paller, Amy S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011393/ https://www.ncbi.nlm.nih.gov/pubmed/27590073 http://dx.doi.org/10.1177/1744806916666284 |
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