A SCN10A SNP biases human pain sensitivity

BACKGROUND: Nav1.8 sodium channels, encoded by SCN10A, are preferentially expressed in nociceptive neurons and play an important role in human pain. Although rare gain-of-function variants in SCN10A have been identified in individuals with painful peripheral neuropathies, whether more common variant...

Descripción completa

Detalles Bibliográficos
Autores principales: Duan, Guangyou, Han, Chongyang, Wang, Qingli, Guo, Shanna, Zhang, Yuhao, Ying, Ying, Huang, Penghao, Zhang, Li, Macala, Lawrence, Shah, Palak, Zhang, Mi, Li, Ningbo, Dib-Hajj, Sulayman D, Waxman, Stephen G, Zhang, Xianwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011395/
https://www.ncbi.nlm.nih.gov/pubmed/27590072
http://dx.doi.org/10.1177/1744806916666083

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011395/
https://www.ncbi.nlm.nih.gov/pubmed/27590072
http://dx.doi.org/10.1177/1744806916666083

Ejemplares similares