PML at Mitochondria-Associated Membranes Is Critical for the Repression of Autophagy and Cancer Development

The precise molecular mechanisms that coordinate apoptosis and autophagy in cancer remain to be determined. Here, we provide evidence that the tumor suppressor promyelocytic leukemia protein (PML) controls autophagosome formation at mitochondria-associated membranes (MAMs) and, thus, autophagy induc...

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Detalles Bibliográficos
Autores principales: Missiroli, Sonia, Bonora, Massimo, Patergnani, Simone, Poletti, Federica, Perrone, Mariasole, Gafà, Roberta, Magri, Eros, Raimondi, Andrea, Lanza, Giovanni, Tacchetti, Carlo, Kroemer, Guido, Pandolfi, Pier Paolo, Pinton, Paolo, Giorgi, Carlotta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011426/
https://www.ncbi.nlm.nih.gov/pubmed/27545895
http://dx.doi.org/10.1016/j.celrep.2016.07.082

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011426/
https://www.ncbi.nlm.nih.gov/pubmed/27545895
http://dx.doi.org/10.1016/j.celrep.2016.07.082

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