G9a inhibition potentiates the anti-tumour activity of DNA double-strand break inducing agents by impairing DNA repair independent of p53 status

Cancer cells often exhibit altered epigenetic signatures that can misregulate genes involved in processes such as transcription, proliferation, apoptosis and DNA repair. As regulation of chromatin structure is crucial for DNA repair processes, and both DNA repair and epigenetic controls are deregula...

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Detalles Bibliográficos
Autores principales: Agarwal, Pallavi, Jackson, Stephen P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ireland 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011428/
https://www.ncbi.nlm.nih.gov/pubmed/27431310
http://dx.doi.org/10.1016/j.canlet.2016.07.009

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5011428/
https://www.ncbi.nlm.nih.gov/pubmed/27431310
http://dx.doi.org/10.1016/j.canlet.2016.07.009

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